Shannon N Mostyn Selected Research

Glycine Plasma Membrane Transport Proteins

1/2022	Peripheral Administration of Selective Glycine Transporter-2 Inhibitor, Oleoyl-D-Lysine, Reverses Chronic Neuropathic Pain but Not Acute or Inflammatory Pain in Male Mice.
1/2021	The allosteric inhibition of glycine transporter 2 by bioactive lipid analgesics is controlled by penetration into a deep lipid cavity.
1/2020	Photoswitchable ORG25543 Congener Enables Optical Control of Glycine Transporter 2.
10/2019	Identification of an allosteric binding site on the human glycine transporter, GlyT2, for bioactive lipid analgesics.
1/2019	Development of an N-Acyl Amino Acid That Selectively Inhibits the Glycine Transporter 2 To Produce Analgesia in a Rat Model of Chronic Pain.
1/2017	Synthesis and Characterization of Novel Acyl-Glycine Inhibitors of GlyT2.

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Shannon N Mostyn Research Topics

Disease

5	Chronic Pain 01/2022 - 01/2019
4	Pain (Aches) 01/2022 - 01/2017
2	Hyperalgesia 01/2022 - 01/2020
1	Acute Pain 01/2022
1	Neuralgia (Stump Neuralgia) 01/2022
1	Respiratory Insufficiency (Respiratory Failure) 01/2022
1	Hypersensitivity (Allergy) 01/2020
1	Nervous System Diseases (Neurological Disorders) 01/2016

Drug/Important Bio-Agent (IBA)

6	Glycine Plasma Membrane Transport ProteinsIBA 01/2022 - 01/2017
5	Glycine (Aminoacetic Acid)FDA LinkGeneric 01/2022 - 01/2016
3	LipidsIBA 01/2022 - 10/2019
2	Analgesics (Analgesic Drugs)IBA 01/2021 - 10/2019
1	Freund's AdjuvantIBA 01/2022
1	Lysine (L-Lysine)FDA Link 01/2022
1	Opiate AlkaloidsIBA 01/2022
1	4- benzyloxy- 3,5- dimethoxy- N- (1- (dimethylaminocyclopently)methyl)benzamideIBA 01/2022
1	Amino Acids FDA Link 01/2019

Therapy/Procedure

4	Analgesia 01/2022 - 01/2017